In the 1930s and 40s, human sacrifice as offering to the gods was still practiced in some remote areas of the world. Such inhuman act itself is already a huge delusion which can only increase, not overthrow, our ignorance.
Once there is ignorance, there is attachment—attachment to the outer world, to one’s own body, reputation, interest, etc. When failing to satisfy one’s desire, negative emotions arise and one suffers. In order to satisfy all the desires, one may resort to evil ways. Thus, all evil karma comes from attachment and ignorance.
~ Depicted from "THE HANDBOOK FOR LIFE"S JOURNEY : On The Three Poisons - How to Refute Ignorance